The procedure of Intra Cytoplasmic Sperm Injection (ICSI) is used as an extra step in an IVF cycle for couples in certain circumstances where a major male factor exists and calls for a possible male infertility treatment. It involves the capture and selected injection of a single sperm into an oocyte(egg) retrieved during an IVF cycle by a scientist with a high powered microscope and high tech injection system. The procedure requires exceptional skill and training but can make the difference when the fertilisation of an egg by sperm can’t happen without assistance in the laboratory. There are many clinical situations which may necessitate the procedure, some have clear causes some are not easily explained.
There was some initial concern that ICSI might bypass yet another step in natural selection and lead to an increase in abnormalities. This has effectively been disproven after many years of experience and close follow-up of pregnancy outcomes however we continue to monitor the effects of the procedure.
As clinicians we still look for specific indications to justify the use of the technology.
The usual indications for ICS are as follows:
1. The sperm concentration is reduced (particularly below 10 million/ml)
2. The motility of sperm is poor
3. There are elevated proportions of abnormal sperm (head , body, tail or combination defects with <4% normal)
4. Testicular aspirated sperm (via TESE) after vasectomy or congenital absence of the Vas Deferens (CBAVD)
5. Previous poor fertilisation results with IVF
6. High level anti-sperm antibodies
7. Some cases of bladder retrieved sperm in retrograde ejaculation
8. Considered in some couples with low numbers of oocytes and/or maternal age > 40
9. In association with certain PGD procedures
10. Some other indications based on individual circumstances and clinical recommendations.
Intra-Cytoplasmic Sperm Injection or (ICSI) is the most successful form of treatment for men who are infertile, and can be used as part of an IVF treatment to help you and your partner conceive a child. You should consider undergoing Intra-Cytoplasmic Sperm Injection if you find out through your doctor that you have male fertility problems.
Intra-Cytoplasmic Sperm Inject is used in cases of severe male infertility, including men with a very low spem count, those who have abnormally shaped sperm or men who have poor sperm movement. It is used as part of IVF treatment.
Trouble getting pregnant is a symptom of male fertility problems, and can be detected through tests, which in turn can uncover things like low or zero sperm count, problems getting an errection and ejaculating due to such issues like spinal cord injuries, sexual disfunction and diabeties amoung other things.
Inta-Cytoplasmic Sperm Injection may be used as part of an IVF treatment. Women take ovarian stimulating drugs and after egg retrieval, the male is asked to supply a sperm sample the same day. Fertilisation takes place outside the body and if embrologist thinks that the embryo is healthy, it will be transfered to the womb between two and five days after retrieval.
Intra-Cytoplasmic Sperm Injection isn’t the solution to every male ferlility problem. ICSI is likely to be recommended by a specialist such as Dr Gary Swift who practices at QFG Gold Coast Fertility Clinic if you or your partner has fertility problems. Intra-Cytoplasmic Sperm Injection can be useful if you have previously undergone a vasectomy but have decided you now want children or to have more children.
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